How we decide which questions to answer.
J. D. CLOUGH

  Brief answers to specific clinical questions

 Are strict vegetarians at risk of vitamin B12 deficiency?
Patients who avoid or limit animal products in their diets should be encouraged to take vitamin B12 supplements or eat fortified foods.
M.A. NOVY

 Is there an advantage to combination therapy with ACE inhibitors and angiotensin II receptor blockers?
Theoretic reasons and small studies suggest the two types of drugs may be useful in combination, but a definitive answer awaits the results of larger studies.
D.G. VIDT

Antiviral drugs for treating influenza
We now have four antiviral drugs for treating influenza. Who should receive them? Which one to use?
J.K. LONG, S.B. MOSSAD, and M.P. GOLDMAN

The spectrum of nonalcoholic fatty liver disease:From steatosis to nonalcoholic steato- hepatitis
This recently discovered disease is a common cause of elevated liver enzymes. We are beginning to understand which patients are at greatest risk of progressive liver disease.
S. SAADEH and Z.M. YOUNOSSI

Psoriasis: A clinical update on diagnosis and new therapies
A framework for recognizing the many forms of psoriasis and a logical approach to therapy, which now includes, in severe cases, powerful immunosuppressive drugs.
C. CAMISA

Brain metastases: Presentation, evaluation, and management
Prompt diagnosis and treatment can prolong the patient's life and improve the quality of his or her remaining days.
M.A. CHIDEL, J.H. SUH, and G.H. BARNETT

 Update On Acute Coronary Syndromes .....................................................................

Glycoprotein IIb/IIIa inhibitors in acute coronary syndromes
These potent antiplatelet agents constitute a breakthrough, but questions remain about their safety, cost-effectiveness, and proper empiric use. With an illustration explaining the paradoxical prothrombotic effect of fibrinolytic drugs.
M.T. ROE, S.K. SAPP, and A.M. LINCOFF