AIDS update
1999:
Viral reservoirs and immune-based therapies
C. Isada and L.H.
Calabrese
Abstract
The advent of highly active antiretroviral therapy (HAART)
has brought about a dramatic decline in opportunistic infections, hospitalizations, and
mortality in AIDS patients. However, the recent discovery that HIV can lay dormant in
quiescent T cells and other tissues even in the face of HAART therapy has dampened
optimism for a cure for AIDS, though it suggests new avenues of research.
Authors
Carlos M. Isada, MD
Department of Infectious Disease, Cleveland Clinic
Leonard H. Calabrese, DO
Department of Rheumatic and Immunologic Disease
Cleveland Clinic

John D. Clough, M.D., editor-in-chief
Linda K. Hengstler, editor and publisher
Phillip E. Canuto, executive editor
Ray Borazanian, managing editor |