Why effective drugs don't work for everyone
For now, the concept of antiplatelet resistance is useful and probably biologically relevant, but it isn't ready to be incorporated into our clinical practice.
B.F. MANDELL

Mumps surveillance and prevention: Putting mumps back on our radar screen
After the mumps vaccine was introduced, the incidence of mumps fell by 99%. Many of the current generation of physicians have never seen this disease.
M.H. KYAW, W.J. BELLINI, and G.H. DAYAN

Leg weakness in a 66-year-old woman: A common presentation of an uncommon disease
She has proximal leg weakness, weight loss, dry mouth, orthostatic hypotension, and diminished sensation in the arms and legs. What is the likely cause?
A.S. STOJIC, T. MEKHAIL, and B.E. TSAO

Which imaging test for right lower quadrant pain?
A 36-year-old woman presents to the emergency department with abdominal pain and intermittent nausea. You suspect that she has acute appendicitis. Which imaging test should you order to further evaluate this patient?
D.M. HOLDEN and D.M. EINSTEIN

The resurgence of mumps in young adults and adolescents
Outbreaks of mumps in 2005 prompt us to review the salient features and the updated recommendations for vaccination against this once-common disease.
J.D. SHANLEY

Variable response to antiplatelet therapy: What does it mean to clinicians?
Ex vivo tests show that platelet function and response to antiplatelet therapy vary markedly from person to person. But just how clinically significant are these measurements?
N. FALLUJI and S.R. STEINHUBL

Evaluating and managing urinary incontinence after prostatectomy: Beyond pads and diapers
Men who become persistently incontinent after undergoing prostatectomy have a variety of options for regaining control, from behavioral changes to surgery.
H.O. ATIEMO, L. MOY, S. VASAVADA, and R. RACKLEY

Glucosamine in osteoarthritis: Questions remain
Glucosamine is now widely used, but studies have so far failed to prove convincingly that it works, how it might work, or whether it is safe to take long-term.
C.J. LOZADA

The effect of obstructive sleep apnea on chronic medical disorders
Evidence is mounting that obstructive sleep apnea causes or contributes to many chronic medical diseases, and that treatment with continuous positive airway pressure often improves the concomitant diseases.
N. COLLOP

BNP is misleading in patients with a history of heart failure

Carotid stenting is inferior to carotid endarterectomy

DHEA and testosterone are not effective in aging patients

Rosiglitazone delays the development of diabetes mellitus (DREAM trial)

Letter to the Editor
Primary progressive aphasia (November 2006)

Correction
PET and PET/CT imaging (December 2006)