A syringe in the hand is worth two birds in the bush
Short of a true pandemic, there is much we can do to make the 2005-2006 flu season a kinder, gentler one.
B.F. MANDELL

DHEA supplementation: The claims in perspective
Low DHEA levels are seen in a variety of diseases, but whether supplemental DHEA will help remains unproven.
E. OLECH and J.T. MERRILL

Safety of statins: Effects on muscle and the liver
Hepatotoxicity and myopathy are uncommon but worrisome. ALT and AST should be measured at baseline and periodically during statin therapy.
A.R. VASUDEVAN, Y.S. HAMIRANI, and P.H. JONES

Hepatitis C infection: A systemic disease with extrahepatic manifestations
Almost 40% of patients with hepatitis C develop at least one extrahepatic manifestation during the course of the disease.
A. ALI and N.N. ZEIN

A 73-year-old woman with chronic nonhealing cellulitis
She has undergone extensive treatment with antibiotics and corticosteroids, without success. What is the likely diagnosis?
A.K. LEUNG and W.S. ARMSTRONG

Anemia in chronic heart failure: Can EPO reduce deaths?
Many patients with chronic heart failure also have anemia, but whether treating the anemia will improve outcomes has yet to be determined.
S. IYENGAR and W.T. ABRAHAM

What is a 'failure' of bisphosphonate therapy for osteoporosis?
Assessing the effectiveness of bisphosphonate therapy is problematic. The true measure is prevention of new fractures.
J.J. CAREY

Influenza 2005-2006: Vaccine supplies adequate, but bird flu looms
Behind the preparation for the current influenza season are fears that the simmering outbreak of avian influenza in animals could lead to a pandemic in humans.
S.B. MOSSAD

A 39-year-old man with sudden onset of chest pain
He has a history of a transient ischemic attack and poorly controlled hypertension. What is the likely diagnosis?
P.R. SUNKUREDDI, E.B. GONZALEZ, R. WASHINGTON, A. SALAZAR, and P. DOUGLASS

Guideline for chronic constipation management

Metformin increases fertility in polycystic ovary syndrome

Clinical assessment is of limited value in DVT diagnosis

Pulmonary artery catheters: No harm, no benefit

Letter to the Editor
Pulmonary embolism imaging