Antiaging therapies: High hopes, little evidence

    Long-acting beta agonists for asthma: The controversy

    ASTEROID trial: High-dose statins shrink coronary lesions

    What to expect from bariatric surgery

    Telling bipolar disorder from unipolar depression in primary care

    Osteoarthritis:

  • Intra-articular steroids
  • Intra-articular hyaluronans
  • Does glucosamine work?

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    The Cleveland Clinic Foundation
    Cleveland Clinic Journal of Medicine
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    The Journal, the Internet, and you
    At ccjm.org you can find all of our articles, free CME credit, and now the proceedings of the second annual Cleveland Clinic Perioperative Medicine Summit.
    B.F. MANDELL

     

    When should prophylactic anticoagulation begin after a hip fracture?
    The short answer is immediately, but several issues need consideration before starting.
    P.J. GRANT and A.K. JAFFER

     

    Migraine prophylaxis: Who, why, and how
    If a patient has frequent, severely debilitating migraine headaches, prophylactic treatment may help. But only about half of patients obtain a 50% or greater reduction in attacks.
    J. LOJ and G.D. SOLOMON

     

    Is digoxin a drug of the past? This old drug is still useful, with some caveats.
    It is no longer the cornerstone of heart-failure treatment, but it can be beneficial as an adjunct. Serum levels should probably be kept lower than in the past.
    M.H. PERVAIZ, M.G. DICKINSON, and M. YAMANI

     

    Tending to the musculoskeletal problems of obesity
    Obese patients often hear that any ache or pain they have is due to their excess weight and will resolve with weight loss. The truth is more subtle, but weight loss can make a substantial difference.
    M.M. HOOPER

     
    Newer antibiotics for serious gram-positive infections
    We use two case scenarios to discuss when and how to use these agents and how to monitor and respond to their adverse effects.
    T.G. FRASER, C. HANSEN, and J.K. LONG
     

    Imaging's roles in acute pancreatitis
    A 50-year-old man presents with severe upper-abdominal pain radiating to the back with nausea and vomiting. His serum amylase and lipase levels are markedly elevated. Should he have any imaging tests, and if so, which ones?
    T. BOLEK, M.E. BAKER, and R. MATTHEW WALSH

     

    A perspective on the Women's Health Study: Aspirin prevents stroke but not MI in women; vitamin E has no effect on CV disease or cancer
    This 10-year trial found that aspirin prevented stroke but not myocardial infarction in women. Vitamin E had no effect.
    J.E. BURING

     

    Metformin helps kids lose weight