Adverse drug reactions and medication errors: Not always a clear distinction. 
Unrecognized adverse drug reactions can quickly become medication errors.
J.D. CLOUGH

Acute onset of knee pain
J. SCHILS and M. KLINE

A young person with papules and plaques
K.J. TOMECKI and A.R. KOOKEN

Should amphetamines be added to SSRI therapy to enhance the antidepressant effect?
Despite anecdotal reports of an additive effect, no firm conclusions can be drawn.
V. SINGH and D. MALONE

At what level of hyperkalemia or creatinine elevation should ACE inhibitor therapy be stopped or not started?
These drugs are a double-edged sword: they slow the decline in renal function in many patients, yet reduce renal function in some.
S. NURKO

Physician’s guide to popular low-carbohydrate weight-loss diets
These diets can take pounds off fast but usually fail in the long term and can jeopardize health.
G.L. BLACKBURN, J.C.C. PHILLIPS, and S. MORREALE

The dangers of self-monitored dieting: What are our patients really doing?
Patient-monitored diets often leave questions of adherence and safety unanswered.
C.L. MOORE

Drug-induced lung disease
Early diagnosis is important because stopping the drug usually reverses toxicity, whereas unrecognized toxicity can be progressive and even fatal.
M. ÖZKAN, R.A. DWEIK, and M. AHMAD

In-stent restenosis: Update on intracoronary radiotherapy
Intracoronary radiotherapy at the time of repeat balloon angioplasty is proving effective in treating in-stent restenosis and lowering rates of recurrence.
A.W. CHAN and D.J. MOLITERNO

New developments in long-term treatment of HIV: The honeymoon is over
New recommendations advise starting antiretroviral therapy slightly later in the course of HIV disease than did earlier guidelines, as treatment has serious long-term side effects.
C.M. ISADA

NEW SERIES Cardiovascular Board Review
The first installment of a new series makes its debut in this issue.
C. RIMMERMAN and B.P. GRIFFIN

Systolic ejection murmur presenting with dyspnea on exertion
What is the cause of this patient’s cardiac symptoms? A self-test.
T. PEIKERT, C.R. ASHER, and B.P. GRIFFIN